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Longvida® Optimized Curcumin Receives GRAS Determination
August 23rd 2012 -
Noblesville, IN., August 20, 2012 – Verdure Sciences received Generally Recognized as Safe (GRAS) status for Longvida® Optimized Curcumin. The safety determination, conducted by an independent, internationally recognized expert panel of scientists, is based on more than a dozen clinical, preclinical and safety studies on Longvida®, along with scores of supporting studies on curcumin by a number of government and university research groups.
As a result of the assessment, Longvida® has been determined as a safe additive for a variety of foods and beverages when used as a flavoring agent (flavor enhancer) [21 CFR§170.3(o)(11)] and as an antioxidant in various food categories, including but not limited to use in the following product types:
As a result of the GRAS determination, safe usage levels of 0.2% to 1.25% of Longvida® were recommended across a range of food and beverage categories.
“We are pleased to receive this independent safety assessment of Longvida®,” said Blake Ebersole, Technical Director at Verdure Sciences. “The substantial evidence supporting the safety and efficacy of Longvida®, particularly at low-dose levels makes it an ideal ingredient for food and beverage products.”
In published 90-day subchronic toxicity study included in the GRAS assessment, Longvida® showed no toxicity at 720 mg/kg body weight/day, the highest dose tested (1). This dose is 100 times the dosage range recommended for human use, after adjusting for body weight. Longvida® adheres to the most stringent global standards for impurities, and contains no piperine, crude lecithin, volatile oils, gluten, sugar, salt, artificial preservatives or additives.
The GRAS determination also covers Longvida® SD, a form of Longvida® which is one of the first forms of curcumin that is easily water-dispersible in solution for food and beverage applications.
About Longvida® Optimized Curcumin:
Based on patent pending discoveries from the University of California-Los Angeles (UCLA), Longvida® Optimized Curcumin is the result of numerous clinical and scientific studies, many published in renowned academic journals (2). Recently, a randomized, placebo-controlled clinical trial conducted at The Ohio State University determined that a single low-dose Longvida® improved a number of biomarkers in just 30 days, including amyloid-beta, a key biomarker responsible for brain aging (3). www.longvida.com
About Verdure Sciences:
2. Longvida Scientific References, http://www.longvida.com/Curcumin-References-and-Links.html accessed August 13, 2012
3. Disilvestro R. Diverse effects of a low-dose supplement of lipidated curcumin (Longvida®) in healthy middle aged people. FASEB, April 23 2012.
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